Table 2.
Results of validated instruments, history, and physical findings analyzed by menopausal status
| All patients (N = 140) | Premenopausal (n = 70) | Menopausal (n = 70) | |
|---|---|---|---|
| Age (range = 18–77 y), median | 45 | 31 | 58 |
| Duration of sexual dysfunction (y), median | 6 | 6 | 6 |
| FSFI scores, median | 15.4 | 15.2 | 15.8 |
| Desire | 2.4 | 2.4 | 2.4 |
| Arousal | 2.7 | 2.4 | 3 |
| Lubrication | 2.4 | 2.4 | 2.3 |
| Orgasm | 2.4 | 1.6 | 3.2 |
| Pain | 1.2 | 1.2 | 1.6 |
| Satisfaction | 2.4 | 2.2 | 2.8 |
| SDS-R score, median | 31 | 35 | 25 |
| PSS score, median | 21 | 22 | 21 |
| PHQ scores, median | 6 | 7 | 5 |
| Sensory | 7 | 11 | 3 |
| Affective | 2 | 3.5 | 0 |
| PPI score, median | 3 | 3 | 2 |
| V-Q score, median | 6.5 | 8.5 | 3 |
| Total T, median | 23 | 23 | 22.1 |
| SHBG, median | 78 | 85 | 77 |
| Calculated free T, median | 0.245 | 0.240 | 0.249 |
| Clitoral pain, n (%) | 20 (14.3) | 13 (18.6) | 7 (10) |
| PGAD, n (%) | 11 (7.9) | 4 (5.7) | 7 (10) |
| Yeast infection Hx, n (%) | 99 (70.7) | 49 (70.0) | 50 (71.4) |
| UTI Hx, n (%) | 79 (56.4) | 40 (57.1) | 39 (55.7) |
| Perineal trauma Hx, n (%) | 33 (23.6) | 22 (31.4) | 11 (15.7) |
| Lichen sclerosus Hx, n (%) | 8 (5.7) | 5 (7.1) | 3 (4.3) |
| Lysis of adhesions, n (%) | 6 (4.3) | 3 (4.3) | 3 (4.3) |
FSFI = Female Sexual Function Index; Hx = history; PGAD = persistent genital arousal disorder; PHQ = Personal Health Questionnaire; PPI = Present Pain Intensity; PSS = Perceived Stress Scale; SDS-R = Sexual Distress Scale–Revised; SHBG = sex hormone binding globulin; T = testosterone; UTI = urinary tract infection; V-Q = Vulvar Pain Questionnaire.