Table 4.

Vulvoscopic photo scoring of vulva, vestibule, and vagina in women before and at completion of 20 weeks therapy with ospemifene 60 mg/d

Parameter	Week 0, median (IQR)	Week 20, median (IQR)	P value
Loss of labia majora	0 (0–0)	0 (0–0)	.32
Loss of labia minora	1 (1–1.5)	1 (1–1)	.16
Decreased size of glans clitoris	1 (1–2)	1 (1–1.5)	.32
Prominence of urethral meatus	2 (2–2)	1 (1–1.5)	.025
Stenosis of introitus	2 (2–2.5)	1 (1–1.5)	.0102
Vestibular pallor	2 (2–2)	1 (1–1)	.0067
Vestibular erythema	2 (2–2)	1 (0.5–1)	.0083
Loss of vestibular moisture	2.5 (2–3)	1 (1–1)	.0124
Loss of vaginal rugae	2 (1.5–2)	1 (1–1.5)	.047
Loss of prominence of the anterior vaginal wall	2 (1.5–2)	1 (1–1)	.027
Total score	17.5 (16–18.5)	9.5 (8–11.5)	.0115

IQR = interquartile range.