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. 2018 May 4;20(5):e162. doi: 10.2196/jmir.9751

Table 3.

Quality of evidence of glycated hemoglobin (HbA1c).

Outcome Number of participants (number of studies) Standardized mean differences (95% CI) Quality of evidence (GRADEa)
HbA1c short term 251 (3) −0.50 (−0.91 to −0.08) Lowb,c
HbA1c long term 452 (4) −0.24 (−0.43 to −0.06) Moderated

aGRADE: Grading of Recommendations Assessment, Development, and Evaluation.

bDowngraded because of risks of biases (such as attrition bias, blinding, and other bias).

cDowngraded because of imprecision (few participants, less than 300).

dDowngraded because of imprecision (variation in the estimate of effect).