Fig. 1.

Characterization of BSA-containing PLGA microspheres. Scanning electron microscopy images of particles formed with (A) Formulation C, (B) Formulation G, and (C) Formulation E, demonstrating spherical and smooth morphology. Small microspheres may be underrepresented in these images due to their tendancy to accumulate beneath the curvature of larger particles during sample preparation. Histograms depiciting the size distribution of microspheres prepared with (D) Formulation C, (E) Formulation G, and (F) Formulation E as well as the volume distribution of (G) Formulation C, (H) Formulation G, and (I) Formulation E microspheres.