Table 1.

Microsphere formulations and size characterization.

Formulation	BSA (% w/w)	PLGA Mw (kDa)	PLGA ratio	Particle size (µm)	90% Threshold diametera (µm)
A	5	7–17	50:50	10.5 ± 6.8	18.5
B	3	7–17	50:50	10.6 ± 6.4	18.1
C	0.5	7–17	50:50	10.3 ± 6.2	22.1
D	0	7–17	50:50	10.5 ± 5.9	17.4
E	5	24–38	50:50	8.6 ± 6.7	21.4
F	3	24–38	50:50	11.4 ± 8.3	21.4
G	0.5	24–38	50:50	12.1 ± 8.2	23.1
H	0	24–38	50:50	11.4 ± 7.2	20.2
I	5	38–54	50:50	14.1 ± 9.4	25.4
J	3	38–54	50:50	12.0 ± 7.1	20.3
K	0.5	38–54	50:50	11.9 ± 6.8	20.6
L	0	38–54	50:50	11.9 ± 6.4	19.7
M	5	4–15	75:25	11.3 ± 7.0	19.7
N	3	4–15	75:25	12.2 ± 7.4	21.2
O	0.5	4–15	75:25	12.4 ± 7.5	21.1
P	0	4–15	75:25	11.7 ± 6.5	19.9

^a90% of particles in the formulation are smaller than this threshold.