Table 2.
Sensitivity, specificity, predicative values of optical microscopy (OM) and NADAL® Malaria Test 4 species with PCR as gold standard
| Positive PCR (n = 160) | Negative PCR (n = 72) | Sensitivity % (CI95) | Specificity % (CI95) | PPV % (CI95) | NPV % (CI95) | |
|---|---|---|---|---|---|---|
| Microscopy | ||||||
| Positive (n = 112) | 108 | 4 | 68.8 (60.5–75.5) | 94.4 (86.4–98.5) | 96.4 (91.2–98.6) | 57.6 (51.8–63.3) |
| Negative (n = 118) | 50 | 68 | ||||
| Missing (n = 2) | 2 | |||||
| NADAL test | ||||||
| Positive (n = 112) | 105 | 7 | 65.6 (57.7–72.9) | 90.3 (81.0–96.0) | 93.8 (88.0–96.8) | 54.2 (48.5–59.7) |
| Negative (n = 120) | 55 | 65 | ||||
| P-value = 0.212* | ||||||
PVP positive predictive value, NVP negative predictive value, CI95 95% confidence interval
* DeLong’s test for two correlated ROC curves with AUCmicroscopy = 81.6% and AUCNADAL test = 80.0%