Table 2.

The relationships between methylation status at 2 months and pre- and postnatal environments

CpG no.	2	3	4	5	8	9	10	11
Gc circ	0.568	0.877	0.968	0.754	0.715	0.855	0.66
SD	− 0.547						− 0.352
Gc CLD	− 0.365				0.327
AS	− 0.193				− 0.298	− 0.254
Bf								− 0.492
Adjusted R2	0.922	0.774	0.933	0.544	0.752	0.858	0.724	0.198
Overall p	※	※	※	※	※	※	※	0.032
CpG no.	12	15	16	17	18	19	23	24
Gc circ	0.802	0.789	0.837	0.755	0.887	0.842	0.894	0.639
SD		− 0.255	− 0.234	− 0.285				− 0.364
Gc CLD
Bf
Adjusted R2	0.623	0.838	0.909	0.811	0.89	0.691	0.788	0.702
Overall p	※	※	※	※	※	※	※	※
CpG no.	25	26	31	32	33	34	36	39
Gc circ	0.81	0.865	0.908	0.877	0.892	0.902		0.827
SD	− 0.246
Gc CLD
AS
Bf							− 0.506
Adjusted R2	0.869	0.734	0.814	0.756	0.784	0.803	0.213	0.665
Overall p	※	※	※	※	※	※	0.027	※

Regression coefficients of independent variables are shown. A blank means not extracted as independent variables

Gc circ glucocorticoid administration for circulatory collapse, SD SD score of birth weight, Gc CLD glucocorticoid administration for CLD, AS antenatal glucocorticoid administration, Bf amount of human milk

^※p < 0.001