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. Author manuscript; available in PMC: 2018 May 19.
Published in final edited form as: Anal Chem. 2018 Jan 8;90(3):1870–1880. doi: 10.1021/acs.analchem.7b03949

Figure 2.

Figure 2

High-pH trapping improves the S/N ratio more than low-pH trapping. (a) Comparison of S/N for the 10 proteins in tissue or plasma by high-pH or low-pH trapping. The concentrations were ∼10× the limit of detection (LOD) for each protein. (b,c) Representative chromatograms from high-pH and low-pH trapping.