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Localization of functionally validated NMDAR subunit mutations in epilepsy
| GRIN1 | GRIN2A | GRIN2B | GRIN2D | Sum | |
|---|---|---|---|---|---|
| ATD | 0 | 4 | 0 | 0 | 4 |
| LBD-S1 | 0 | 7 | 3 | 0 | 10 |
| S1-M1 linker | 3 | 3 | 0 | 0 | 6 |
| TM1 | 0 | 0 | 0 | 0 | 0 |
| TM2 | 0 | 1 | 2 | 0 | 3 |
| TM3 | 2 | 1 | 0 | 1 | 4 |
| M3-S2 linker | 0 | 0 | 0 | 0 | 0 |
| LBD-S2 | 0 | 11 | 0 | 0 | 11 |
| S2-M4 linker | 0 | 2 | 0 | 0 | 2 |
| TM4 | 2 | 1 | 0 | 0 | 3 |
| CTD | 1 | 2 | 0 | 0 | 3 |
| Sum | 8 | 32 | 5 | 1 | 46 |
