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. 2018 Apr 2;34(3):507–516. doi: 10.1007/s12264-018-0221-y

Fig. 1.

Fig. 1

Effects of ZNF804A rs1344704 on left hippocampal-frontal functional connectivity. A Frontal region (red box) with a significant genotype main effect for functional connectivity from the left hippocampus to the right dorsolateral prefrontal cortex (DLPFC) (peak MNI coordinates: x = 21, y = 42, z = 33, peak F-score = 13.43, P < 0.001, cluster size = 19). The color bar indicates the F-score. B Scatterplot of the mean strength of resting-state functional connectivity (RSFC) (mean ± SD) between the left hippocampus and the frontal region in the genotype groups. The Y-axis indicates the Z-score. C Scatterplot of the mean strength of RSFC (mean ± SD) from the left hippocampus to the right DLPFC in the genotype groups (CC/CA and AA genotype groups) in different diagnostic groups. The Y-axis indicates the Z-score. SZ, schizophrenic patients; HC, healthy controls; lHIPP, left hippocampus; rDLPFC, right dorsolateral prefrontal cortex; *P < 0.05, **P < 0.01, ***P < 0.001.