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. 2018 May 3;9(5):416–431. doi: 10.1007/s13238-018-0549-0

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Metaorganismal pathway of trimethylamine N oxide (TMAO) biosynthesis and linking to cardiovascular disease. FMOs, Flavin monooxygenases. R1, R2, CH₃(CH₂)n₁(CH=CH)n₂, n₂ = 0, 1, 2…..6, n₁ + 2n₂ = 15, 17, 19, 21