Fig. 2.

JCT dose–response of CFTR channel in HEK293T cells transiently transfected with CFTR. a Representative time courses of the JCT evoked whole-cell currents recorded at +100 and −100 mV under ramp clamp. b Corresponding I–V relationships at time points a, b, c, d and e. c Peak current densities induced by JCT normalized to that of 10 μM FSK (n = 5–8). Data points show the mean ± S.E.M