Fig. 5.
DEC lines (MBN1/MBN2and MBN/MBDMD) improve muscle force 90 days after intramuscular transplant to GM of mdx/scid mice. In situ muscle force (a) fatigue tolerance (b) and ex vivo muscle force under maximal sine wave stimulation (c) and maximal percent strain (d) in GM of vehicle, not-fused MB, and chimeric cells MBN1/MBN2 and MBN/MBDMD injected mdx/scid mice. Muscle force was normalized by the isolated GM weight. (a, b; n = 4) (c, d; n = 3) p = 0.04, One-way Anova with Tukey post-hoc test