. 2018 May 3;2018:9863050. doi: 10.1155/2018/9863050

Table 1.

Change of biochemical parameter during 1 year of antithyroid treatment.

	Baseline	4 wk	8 wk	12 wk	26 wk	52 wk
Free T4 (ng/dL)	3.32 ± 1.46	2.00 ± 0.87 ^∗	1.28 ± 0.61 ^∗	1.38 ± 0.72 ^∗	1.00 ± 0.22 ^∗	1.10 ± 0.25 ^∗
Total T4 (μg/dL)	16.0 ± 5.5			7.6 ± 4.2 ^∗	6.2 ± 1.5 ^∗	7.8 ± 1.9 ^∗
Free T3 (ng/dL)	2.21 ± 1.63			0.57 ± 0.47 ^∗	0.38 ± 0.08 ^∗	0.40 ± 0.13 ^∗
Total T3 (ng/dL)	295 ± 140	206 ± 88 ^∗	131 ± 45 ^∗	137 ± 74 ^∗	109 ± 28 ^∗	107 ± 34 ^∗
TSH (μIU/mL)	0.01 ± 0.00	0.01 ± 0.00	0.06 ± 0.10	0.99 ± 0.99	3.30 ± 5.74	1.74 ± 1.66 ^∗
TSH receptor antibody (IU/L)	17.99 ± 13.65	14.13 ± 13.87	12.15 ± 12.79	10.97 ± 12.99	7.65 ± 9.43	4.43 ± 4.92
Peripheral deiodinase activity^a ( ${\hat{G}}_{D}$ , nmol/s)	156 ± 78			84 ± 31 ^∗	79 ± 12	76 ± 17
Thyroid's secretory capacity^a ( ${\hat{G}}_{T}$ , pmol/s)	623 ± 215			165 ± 259 ^∗	95 ± 142 ^∗	76 ± 179 ^∗
Total cholesterol (mg/dL)	158 ± 46			210 ± 53 ^∗	203 ± 46 ^∗	221 ± 47 ^∗
Triglyceride (mg/dL)	99 ± 54			85 ± 45	90 ± 34	96 ± 56
HDL cholesterol (mg/dL)	48 ± 9			57 ± 9 ^∗	54 ± 11 ^∗	54 ± 11 ^∗
LDL cholesterol (mg/dL)	90 ± 32			136 ± 41 ^∗	131 ± 31 ^∗	148 ± 37 ^∗
AST (IU/L)	48 ± 31	39 ± 20			21 ± 8 ^∗	20 ± 7 ^∗
ALT (IU/L)	78 ± 71	60 ± 51			19 ± 15 ^∗	21 ± 24 ^∗
ALP (IU/L)	101 ± 60	118 ± 60 ^∗			106 ± 51	62 ± 10

^∗ p < 0.05 compared to baseline values; ^aperipheral deiodinase activity ( ${\hat{G}}_{D}$ ) and thyroid' secretory capacity ( ${\hat{G}}_{T}$ ) were calculated with the equations described in Materials and Methods.