Figure 5.

March1 deficiency leads to less antibody production against OVA in the ovalbumin-allergic model. Total IgE (a), OVA-specific IgE (b), and OVA-specific IgG₁ (c) were measured in the serum of WT and March1^−/− mice. ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001, ^#p < 0.1 (trend). Data are pooled from 4 independent experiments and presented as mean with SEM (a, b); n = 4–7. In (c) (IgG1), data are pooled from 7 independent experiments and presented as median with interquartile values; n = 8–14.