Figure 7.

The OVA challenge of immunized mice is associated with an increase in the number of lung CD88^Interm. alveolar macrophages and CD88-positive lymphocytes relative to sham-sensitized groups in the two strains, the magnitude of which is reduced in the absence of March1. CD88-expressing lung lymphocytes were identified by flow cytometry (a). Alveolar macrophages were identified as in Figure 1(a). The numbers of CD88^Hi and CD88^Interm alveolar macrophages were expressed as absolute numbers (b). Absolute numbers of CD88-positive T cells and B lymphocytes are shown in (c). ^∗ denotes statistically significant, ^#p < 0.1 (trend). Data are pooled from 3 independent experiments and presented as mean with SEM; n = 5–8/group.