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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Abdom Radiol (NY). 2018 Jul;43(7):1575–1582. doi: 10.1007/s00261-017-1389-8

Table 3.

Spearman’s Rank Correlations for absolute post-therapeutic values for MRI parameters with percentage tumor response in histopathology and 95% CI.

Reader 1
Pre-treatment values Post-treatment values Delta (post-pre) values
Parameter Rho p-value Rho p-value Rho p-value
DWI volume −0.25 (−0.61, 0.21) 0.28 −0.57(−0.79, −0.22) 0.007 −0.58 (−0.80, −0.23) 0.009
ADC −0.09 (−0.50, 0.36) 0.71 −0.12 (−0.50, 0.30) 0.60 −0.08 (−0.34, 0.47) 0.60
DCE volume −0.18 (−0.54, 0.24) 0.40 −0.55 (−0.78, −0.18) 0.006 0.07 (−0.88, 0.49) 0.86
Ktrans −0.18 (−0.54, 0.24) 0.40 −0.32 (−0.64, 0.09) 0.12 −0.36 (−0.04, 0.67) 0.08
TLP (n=24) −0.28 (0.62, 0.14) 0.18 −0.36 (−0.66, 0.05) 0.09 0.13 (−0.29, 0.51) 0.55
TLD (n=21*) −0.25 (−0.62, 0.20) 0.28 −0.55 (−0.80, −0.16) 0.009 0.14 (−0.31, −0.54) 0.56

Reader 2
Pre-treatment values Post-treatment values Delta (post-pre) values
Parameter Rho p-value Rho p-value Rho p-value
DWI volume −0.36 (−0.68, 0.09) 0.11 −0.45 (-0.72, −0.06) 0.04 −0.20 (−0.58, 0.25) 0.39
ADC 0.03 (−0.40, 0.46) 0.89 0.02 (−0.39, 0.42) 0.94 −0.06 (−0.48, 0.38) 0.79
DCE volume −0.18(−0.55, 0.24) 0.39 −0.52 (−0.76, −0.15) 0.009 −0.02 (−0.42, 0.39) 0.93
Ktrans 0.07 (−0.34, 0.46) 0.75 −0.28 (−0.61, 0.14) 0.19 0.28 (−0.18, 0.63) 0.19
TLP (n=24) −0.35 (−0.66, 0.06) 0.09 −0.32 (−0.64, 0.09) 0.12 −0.02 (−0.39, 0.42) 0.94
TLD (n=21*) −0.35 (−0.68, 0.10 0.12 −0.59 (−0.81, −0.21) 0.005 0.24 (−0.21, 0.61) 0.29
*

Note: 3 patients missing DWI volume and ADC for both pre and post time points.