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Substitutions in AT1R’s CaM-binding domains
| Domain targeted | Wild-type sequence | Mutant sequence |
|---|---|---|
| SMD2 (AT1R125–141) | DRYLAIVHPMKSRLRRT | DQALAIVHPMKSQLRQT |
| SMD3 (AT1R215–242) | YTLIWKALKKAYEIQKNKPRNDDIFKII | YTLIAKALKKAAEIQKNQPRNDDIAKII |
| SMD4JM (AT1R309–327) | FKRYFLQLLKYIPPKAKSH | AKRYALQLLKAIPPKAQSH |
