Table 9.

Common variable immunodeficiency (CVID) genes with an excess of patients harboring rare functional genetic variants in patients compared to controls.

Gene	Patients functa	Patients no functb	Controls functc	Controls no functd	P-value
PIK3CD	9	25	3	264	1.84E−07
ICOSLG	4	30	6	261	0.018
TNFRSF13B	3	31	4	263	0.034
PIK3R1	2	32	1	266	0.035
CD84	3	31	5	262	0.050
PRKCD	3	31	5	262	0.050

^aNumber of patients with at least one rare functional genetic variant.

^bNumber of patients with no rare functional genetic variants.

^cNumber of controls with at least one rare functional genetic variant.

^dNumber of controls with no rare functional genetic variants.