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. 2018 May 14;11:158. doi: 10.3389/fnmol.2018.00158

Table 3.

Summary of C-type lectins in CNS.

Type Ligands Cell type/Subcellular location Functions References
E-Selectin Sialyl-Lewis X terminal Endothelial cells
  • Plasma membrane

  • Facilitate the adhesion of neutrophils

Jin et al. (2010)
P-Selectin Sialyl-Lewis X terminal Endothelial cells
  • Plasma membrane

  • Facilitate the adhesion of neutrophils

Atkinson et al. (2006) and Jin et al. (2010)
Mannose-binding lectin Terminal mannose, fucose, GlcNAc Microglia
Astrocytes
Oligodendrocytes
Neuron
  • Cytoplasm

  • Extracellular

  • Innate immune defense

Singh et al. (2011)