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. 2018 May 14;11:157. doi: 10.3389/fnmol.2018.00157

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Copyright © 2018 El Soury, Fornasari, Morano, Grazio, Ronchi, Incarnato, Giacobini, Geuna, Provero and Gambarotta.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmap of the 50 most differentially regulated genes in Schwann cells. The heatmap shows the biological triplicate expression of the first 50 differentially expressed genes in Schwann cells stimulated with 10 nM NRG1β1 based on the obtained P value. “Mock” corresponds to samples treated with the vehicle, “treated” corresponds to samples treated with NRG1β1. Colour intensity reflects the expression level and represents the log₂ (RPKM + 1) of the observed gene in each sample (RPKM, Reads Per Kilo base of transcript per Million mapped reads).