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. 2018 May 14;9:933. doi: 10.3389/fimmu.2018.00933

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Copyright © 2018 Butcher, O’Carroll, Wells and Carmody.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of probes induced only by Poly(I:C). (A) Heat map (Pearson correlation) of combined list of top 500 acutely induced genes per acute condition. Color indicates row z-score, ranging from −2 (blue) to 2 (red). Highlight box indicates cluster of probes highly induced only in Poly(I:C). (B) Table of Reactome pathways enriched (adjusted p < 0.05) in genes induced uniquely by acute infection with Poly(I:C). Enrichment: number of genes in test list/number of genes in pathway (adjusted p-value). (C) Table of genes grouped by biological category.