Skip to main content
. Author manuscript; available in PMC: 2018 May 21.
Published in final edited form as: Biochem Soc Trans. 2017 Nov 17;45(6):1313–1321. doi: 10.1042/BST20170095

Figure 1.

Figure 1

Structural arrangement of conserved domains in DEAD-box and DEAH-box helicases. The protein families share two conserved, RecA-like domains with numbered sequence motifs that are highly conserved within each family. Many DEAD-box proteins have additional N- and C-terminal extensions that are required for their specific functions but are not conserved between different DEAD-box proteins and are not shown here. In contrast, DEAH-box proteins share conserved C-terminal domains consisting of winged helix (WH), ratchet-like, and oligosaccharide binding fold (OB fold) domains.