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GLI1 localization. Photoreceptor localization of GLI1 (red) at PN21–28. GLI1 mislocalization within the photoreceptor IS in Ift172fl/fliCre mice, as compared with the mainly OS localization of GLI1 in control mice is visible at PN25. By PN28, GLI1 photoreceptor expression appears largely diminished in Ift172fl/fliCre mice, compared with controls. RP1 (green) marks the transition zone and nuclei are counterstained with Hoechst (blue). The scale bar represents 5 μm.
