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. 2018 Apr 12;27(11):2025–2038. doi: 10.1093/hmg/ddy121

Table 3.

Association between the number of CAG repeats in the AR gene and the mean of the left and right hand 2D:4D ratios

ALSPAC QIMR Meta-analysis
All individuals
N = 5328 N = 498 N = 5826
Mean 0.014 (0.016), P = 0.19 0.040 (0.052), P = 0.22 0.016 (0.015), P = 0.14
High 0.012 (0.015), P = 0.21 0.014 (0.046), P = 0.38 0.012 (0.014), P = 0.20
Low 0.013 (0.016), P = 0.21 0.041 (0.057), P = 0.24 0.015 (0.015), P = 0.16
Male
N = 2615 N = 231 N = 2846
Mean −0.002 (0.020), P = 0.54 −0.099 (0.083), P = 0.88 −0.007 (0.019), P = 0.65
Female
N = 2713 N = 287 N = 3000
Mean 0.046 (0.028), P = 0.05 0.125 (0.072), P = 0.04 0.056 (0.026), P = 0.02
High 0.030 (0.025), P = 0.12 0.068 (0.058), P = 0.12 0.036 (0.023), P = 0.06
Low 0.040 (0.026), P = 0.06 0.112 (0.082), P = 0.09 0.047 (0.025), P = 0.03

Displayed are beta (SE) and P-values in each of the cohorts and the combined estimates from the fixed effects, inverse-variance weighted meta-analysis. ‘Mean’ refers to analyses involving the average CAG repeat length, ‘High’ refers to analyses involving the highest length repeat and ‘Low’ refers to analyses involving the lower length repeat. One-tailed P-values testing for a positive association between CAG repeat length and 2D:4D ratio are presented.