Table 1.

Distant metastatic recurrence rates calculated by Kaplan-Meier estimates for each risk model

	Oncotype DX	TAILORx	AAMC model	P-G algorithm: with RS assay for AAMC Intermediates
Low risk	RS < 18 (n = 703)	RS < 11 (n = 250)	Grade 1 and PR ≥ 1% (n = 322)	AAMC Low plus Intermediates that are RS<18 (n = 739)
	3.4% (95% CI 1.6% to 5.1%, nf = 17)	4.0% (95% CI 0.8% to 7.2%, nf = 8)	2.7% (95% CI 0.0% to 5.4%, nf = 5)	3.3% (95% CI 1.4% to 5.2%, nf = 16)
Intermediate risk	RS 18–30 (n = 424)	RS 11–25 (n = 787)	Not meeting AAMC definition for low or high risk (n = 716)	AAMC Intermediates with RS 18-30 (n = 257)
	15.2% (95% CI 10.3% to 20.1%, nf = 38)	7.3% (95% CI 4.7% to 9.9%, nf = 35)	8.3% (95% CI 5.4% to 11.3%, nf = 36)	12.0% (95% CI 5.8% to 18.1%, nf = 15)
High risk	RS > 30 (n = 141)	RS > 25 (n = 231)	Grade 3 or ER < 20% (n = 230)	AAMC High plus Intermediates that are RS>30 (n = 272)
	23.0% (95% CI 14.7% to 31.3%, nf = 27)	22.9% (95% CI 15.9% to 29.9%, nf = 39)	22.8% (95% CI 16.1% to 29.5%, nf = 41)	24.2% (95% CI 17.9% to 30.5%, nf = 51)

AAMC, The Anne Arundel Medical Center; CI, confidence interval; nf, number of recurrences; P-G, pathologic‐genomic; RS, Recurrence Score.