Table 4.

Poisson Regression Analysis of Predictors of Reporting Severe Adverse Events Among Participants in the Sierra Leone Trial to Introduce a Vaccine Against Ebola

Variables	P a	Incidence Ratio (95% CI)
Vaccination group (vs unvaccinated)	.048
Vaccinated		1.53 (1.00–2.33)
Enrollment month (vs Apr)	.34
August		0.88 (.30–2.58)
July		0.50 (.19–1.32)
June		0.68 (.35–1.31)
May		0.56 (.31–1.02)
Site, district (vs Connaught Hospital, Western Urban)	.014
COMAHS Library, Western Rural		0.78 (.36–1.69)
Port Loko Government Hospital, Port Loko		2.60 (1.32–5.11)
Saint John of God Hospital–Lunsar, Port Loko		1.82 (.64–5.18)
Saint John of God Health Center–Kaffu Bullom, Port Loko		1.89 (.62–5.73)
Holy Spirit Hospital, Bombali		2.01 (1.03–3.92)
Magburaka Government Hospital, Tonkolili		0.74 (.24–2.27)
Age, tertiled (vs 18.0–27.5 y)	.58
27.5–35.4 y		1.01 (.61–1.68)
35.5–79.5 y		0.79 (.46–1.36)
Sex	.29
Female (vs male)		1.34 (.79–2.28)
Occupation (vs frontline worker)	.12
Nurse		0.80 (.39–1.63)
Allied health professional		2.10 (.71–6.22)
Physician, pharmacist, community health worker, laboratory worker		0.16 (.02–1.23)
Surveillance worker		1.27 (.52–3.08)
Other/not reported		1.16 (.48–2.83)
Work site (vs hospital)	.38
Ebola treatment facility		0.69 (.39–1.20)
Clinic setting		0.66 (.35–1.24)
Other/not reported		0.61 (.23–1.62)
Education level (vs tertiary)	.44
None		0.93 (.40–2.19)
Secondary		0.81 (.48–1.39)
Primary		1.07 (.41–2.76)
Other/not reported		4.23 (.97–18.54)

Abbreviations: CI, confidence interval; COMAHS, College of Medicine and Allied Health Sciences, University of Sierra Leone.

^a P values <.05 are given to 3 decimal places.