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. 2018 Mar 13;46(9):4469–4486. doi: 10.1093/nar/gky172

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 9. — DNA/DNA duplex stability, RNA/DNA duplex stability, base stacking energy and posttranslocated state bias for fast (top 500 enrichment values) and slow (bottom 500 enrichment values) sequences for λP_R (A), deoB (B) and UV5 (C). The Y-axis depicts a difference between the average value for fast or slow sequences and the average value for all 262 144 variants of 9 nt sequence. This difference is expressed as a fraction of maximal energy difference from the average within all variants of 9 nt sequence. (D) Correlation between enrichment values and DNA/DNA duplex stability, RNA/DNA duplex stability, base stacking energy and posttranslocated state bias. All energy differences between fast and slow sequences in panels A–C were statistically significant (P-value < 0.0001). All correlation coefficients in panel D (with the exception of posttranslocated state in case of UV5) were statistically significant (P-value < 0.0001).