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. 2018 Mar 12;67(6):1140–1148. doi: 10.2337/db17-1382

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© 2018 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

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Time series of parieto-occipital differences during maintenance. The grand average image compiled from patients and control subjects (far left) illustrates the characteristic parieto-occipital low alpha increase (synchronization) during maintenance, which is thought to reflect the inhibition of incoming visual information. This grand-averaged image was used to identify the peak voxel (14, −80, 25) of this response, and the time series of this voxel was then extracted for group comparisons. This analysis revealed that control subjects had a sustained, stronger low alpha response throughout the maintenance period relative to patients with type 1 diabetes (far right). In this plot, time is shown on the x-axis in ms, amplitude is shown on the y-axis in percent change from baseline, and the gray box reflects the maintenance period where the response amplitude significantly (P = 0.001) differed between groups. L, left; R, right.