Table 3.
Changes in the expression of neuropeptide-encoding genes across conditions in LepRb neurons
| Gene | Change in gene expression (fold) |
|||
|---|---|---|---|---|
| WT 3-h Lep vs. WT PBS | WT 10-h Lep vs. WT PBS | Ob PBS vs. WT PBS | Ob 10-h Lep vs. Ob PBS | |
| Agrp | 0.76 | 1.19 | 5.55 | 0.94 |
| Apoa1 | 1.22 | 1.22 | 2.25 | 1.00 |
| Ghrh | 0.74 | 0.94 | 2.66 | 0.96 |
| Nmb | 0.90 | 0.99 | 4.14 | 0.77 |
| Npy | 0.85 | 1.29 | 4.17 | 0.89 |
| Rbp4 | 0.84 | 0.81 | 1.92 | 0.90 |
| Nts | 0.87 | 1.36 | 0.41 | 1.10 |
| Cartpt | 0.97 | 1.12 | 0.28 | 0.81 |
| Edn3 | 0.64 | 0.82 | 1.85 | 0.77 |
| Gal | 0.93 | 1.60 | 1.01 | 0.98 |
| Kiss1 | 1.14 | 3.29 | 0.46 | 0.97 |
| Ucn | 1.11 | 0.28 | 0.35 | 0.50 |
| Pomc | 1.01 | 1.56 | 0.16 | 1.35 |
Shown are the fold changes in LepRb-enriched transcripts encoding neuropeptides. Lep = leptin, 5 mg/kg i.p. for the indicated time; Ob = Lepob/ob mice. Bolded values are statistically significant between conditions.