Fig. 3. Fluorescence imaging of the cerebrovasculature of mice without craniotomy. (a)–(c) Time-course NIR-IIa images of a control healthy mouse (mouse C1); (d)–(f) PCA overlaid images showing arterial (red) and venous (blue) vessels of mouse C1. (g)–(i) Time-course NIR-IIa images of a mouse with MCAO (mouse M1); (j)–(l) PCA overlaid images showing arterial (red) and venous (blue) vessels of mouse M1. Scale bars: 2 mm. Reproduced from ref. 63 with permission from Springer Nature.