Figure 2. . Correlation between tumor growth inhibition and growth rate inhibition for xenograft tumors of different growth rates.

Tumor growth inhibition and growth rate inhibition show good correlations for slow-growing xenograft tumors. For fast-growing xenograft tumors, growth rate inhibition has a much more dynamic range compared with the tumor growth inhibition, which saturates at around 100%.

GRI: Growth rate inhibition; TGI: Tumor growth inhibition.