Table 1.

I-V Relationship of Ca_V1.2 Isoforms in 5 mM Ba²⁺

Parameters/Splice Isoform	V1/2 (mV)	k	Erev (mV)	n	Gmax (pA/pF)	n
1a/8	−12.9 ± 0.5a	−7.0 ± 0.3	45.5 ± 0.5	9	0.47 ± 0.06d,e	14
1a/8a	−14.4 ± 0.5b	−6.3 ± 0.4	46.9 ± 0.6	11	0.67 ± 0.07c	19
1/8	−15.2 ± 0.7a	−6.0 ± 0.5	47.0 ± 1.0	7	0.93 ± 0.12e	23
1/8a	−18.4 ± 0.7a,b	−5.4 ± 0.5	45.4 ± 0.5	13	1.2 ± 0.1d,c	17

Pooled data are fitted with a combination of a Boltzmann fit and a linear regression either after normalization to its maximal currents or cell capacitance. Half-maximal activation, slope k, and the reverse potential are calculated from the best fit model. The maximal conductance G_max is derived from the current density. All data are represented as mean ± SE. Significance was analyzed by a one-way ANOVA, Bonferroni corrected, ^a/ap < 0.05, ^a/ap < 0.0001, ^b/bp < 0.001, ^c/cp < 0.01, ^d/dp < 0.001, ^e/ep < 0.05.