Table 2.

Physicochemical characters of different QCT-loaded mixed polymeric micelles

Formulation	Polymer ratios	Quercetin (%)	Drug loading (%)	Encapsulation efficiency (%)	Particle size (nm) after centrifugation (10,000 rpm, 10 min) and filtration	PDI	Appearance after storage (−80°C, 2 weeks)	Appearance after lyophilization
A1	P407:TPGS (5:5)	15	3.07	20.45	19.74±0.65	0.189±0.008	Cloudy	Puffy solid mass
A2	L92:TPGS (5:5)	15	5.52	36.83	119.56±2.04	0.184±0.014	Cloudy	Sticky mass
A3	P407:TPGS (7:3)	20	2.95	14.74	108.51±29.54	0.226±0.049	Cloudy	Puffy solid mass
A4	L92:TPGS (7:3)	10	7.57	75.75	178.42±1.78	0.183±0.011	Cloudy	Sticky mass
A5	P123:TPGS (7:3)	15	10.20	68.01	88.56±1.11	0.209±0.011	Cloudy	Sticky mass
A6	L92:TPGS (10:0)	15	12.95	86.39	403.20±140.98	0.267±0.060	Cloudy	Sticky mass
A7	P123:TPGS (10:0)	10	9.47	94.77	82.40±0.98	0.235±0.011	Cloudy	Sticky mass
A8	P407:TPGS (7:3)	10	3.5	35.05	38.45±10.6	0.326±0.030	Cloudy	Puffy solid mass
A9	P123:TPGS (10:0)	20	11.21	56.56	113.62±0.78	0.192±0.002	Cloudy	Sticky mass
A10	P123:TPGS (7:3)	15	10.09	67.32	104.76±1.63	0.277±0.006	Cloudy	Sticky mass
A11	L92:TPGS (7:3)	20	10.14	50.72	168.43±22.74	0.191±0.013	Cloudy	Sticky mass
A12	P407:TPGS (10:0)	15	2.99	19.94	101.5±16.36	0.339±0.032	Cloudy	Puffy solid mass
A13	P123:TPGS (5:5)	20	8.86	44.33	25.07±2.56	0.213±0.016	Cloudy	Sticky mass
A14	P123:TPGS (5:5)	10	7.90	79.04	18.66±0.12	0.157±0.010	Cloudy	Sticky mass
A15	P123:TPGS (7:3)	15	12.88	86.07	95.59±1.19	0.235±0.003	Cloudy	Sticky mass

Abbreviations: QCT, quercetin; PDI, polydispersity index; TPGS, tocopheryl polyethylene glycol succinate.