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. 2018 May 8;114(9):2059–2071. doi: 10.1016/j.bpj.2018.03.035

Table 3.

Table of Free-Energy Cost of Forming a Four-Way Junction in kcal/mol as a Function of the 5′ and 3′ Junction Length in Nucleotide (a and d, Respectively) with the Middle Junction Lengths Fixed (b=c=4nt)

Four-Way Junctions with Center Loops with Lengths b = c = 4 nt
5′ Loop Length (nt), a 3′ Loop Length (nt), d
0 1 2 3 4 5 6 7
0 7.85 (0.43) 7.85 (0.43) 7.60 (0.32) 8.03 (0.53) 8.27 (0.76) 8.03 (0.53) 7.42 (0.27)
1 7.71 (0.37) 8.03 (0.53) 8.27 (0.76) 8.03 (0.53) 8.27 (0.76) 8.03 (0.53) 7.85 (0.43)
2 8.03 (0.53) 8.03 (0.53) 7.85 (0.43) 8.27 (0.76) 7.71 (0.37) 8.27 (0.76) 7.71 (0.37) 7.60 (0.32)
3 8.03 (0.53) 7.85 (0.43) 7.85 (0.43) 7.85 (0.43) 8.03 (0.53) 7.71 (0.37) 7.85 (0.43)
4 7.85 (0.43) 7.71 (0.37) 7.85 (0.43) 8.27 (0.76) 7.85 (0.43) 8.27 (0.76) 8.03 (0.53) 7.85 (0.43)
5 7.71 (0.37) 8.03 (0.53) 7.85 (0.43) 7.71 (0.37) 8.03 (0.53) 7.71 (0.37) 7.42 (0.27)
6 7.71 (0.37) 7.71 (0.37) 8.27 (0.76) 7.71 (0.37) 7.60 (0.32) 7.50 (0.29) 7.60 (0.32)
7 7.50 (0.29) 7.85 (0.43) 7.60 (0.32) 7.42 (0.27) 7.71 (0.37) 8.03 (0.53) 7.85 (0.43) 7.85 (0.43)

Error estimates from the simulation are given in parentheses. Blank entries correspond to events that were not observed during the simulation despite the large size of the ensemble generated.