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Summarized schematic of regrowth process with AFG implantation in rat dorsal semi-section SCI model. For the T9 dorsal hemisection SCI (A), the AFG scaffold was implanted into the injury site to bridge the gap (B). Then, the host cells migrated into the AFG scaffold to replace the aligned structure (C) which supports the axons’ regeneration (D).
Abbreviations: AFG, aligned fibrin hydrogel; SCI, spinal cord injury.
