Table 1.

Correlation of miR-598 and IGF-1R expression with GC clinicopathological variables

Variables	N	miR-598	P-value	IGF-1R mRNA	P-value	IGF-1R protein	P-value
Age
<50	45	3.55±0.45	0.532	10.91±1.11	0.632	1.18±0.16	0.563
≥50	45	3.25±0.51		11.12±1.08		1.03±0.14
Gender
Male	56	3.68±0.31	0.512	12.19±1.31	0.356	1.07±0.17	0.427
Female	34	2.93±0.45		9.04±0.96		1.15±0.14
Tumor size
<5 cm	55	3.76±0.39	0.284	10.03±1.07	0.227	1.03±0.15	0.199
≥5 cm	35	2.83±0.26		12.56±1.35		1.21±0.12
Histological grade
Well/moderate	52	3.77±0.45	0.039*	9.44±0.98	0.045*	0.97±0.10	0.049*
Poor	38	2.89±0.33		13.14±1.65		1.28±0.12
Vascular invasion
Positive	50	2.76±0.29	0.033*	13.37±1.33	0.029*	1.31±0.12	0.028*
Negative	40	4.20±0.43		9.11±0.91		0.84±0.09
Lymph node metastasis
Present	61	2.65±0.35	0.014*	13.31±1.43	0.018*	1.33±0.14	0.007*
Absent	29	4.91±0.47		6.15±0.68		0.66±0.06
TNM stage
I–II	33	4.66±0.56	0.003*	6.89±0.59	0.004*	0.56±0.09	0.002*
III–IV	57	2.67±0.29		13.38±1.66		1.41±0.11

Note:

^*Statistically significant.

Abbreviation: GC, gastric cancer.