Table 2.
The Values of the Activation Energies
| Transitions | 14:1 PC | 16:1 PC | 18:1 PC |
|---|---|---|---|
| State II → Int1 Int1 → Int2 Int2 → State III |
11.4 ± 1.7 13.0 ± 1.0 10.1 ± 2.2 |
10.9 ± 1.3 12.7 ± 2.4 16.6 ± 0.9 |
11.4 ± 1.5 14.1 ± 2.3 21.3 ± 2.2 |
| Total: State II → State III | 34.6 | 40.2 | 46.8 |
The values of the activation energies (Ea, kcal/mol) and St. Er. were calculated for the transitions from State I to Int1; Int1 to Int2; and Int2 to State III along the pHLIP insertion pathway into the lipid bilayer of liposomes of various lipid compositions by fitting of rates (Fig. S5) with Arrhenius function.