The process of deriving SNOMED CT terms from clinical trial eligibility criteria. 42,131 clinical entitieswere extracted from the eligibility criteria of 1,587 clinical trials. A simplified list of 4,260 clinical entities wasgenerated following manual review and filtration, and this list was mapped first to 3,294 UMLS concepts, and then to1,991 SNOMED CT variables, of which 304 variables occur in more than 1% of all trials (i.e., 15 trials).