Table 4.
The top 20 common SNOMED CT terms in AD trials and their prevalence in EHR dataset.
| SNOMED CT Term | SNOMED-CT ID | Trial Count | Prevalence in Trials | Count of usesin EHR data for AD patients |
|---|---|---|---|---|
| Alzheimer’s disease | 26929004 | 972 | 64.29% | 30,262 |
| Mini-mental state examination | 273617000 | 705 | 46.63% | 0 |
| Presenile dementia | 12348006 | 599 | 39.62% | 7,089 |
| Disease | 64572001 | 555 | 36.71% | 12,029,900 |
| Current chronological age | 424144002 | 515 | 34.06% | 0 |
| Mental disorder | 74732009 | 499 | 33.00% | 505,870 |
| Magnetic resonance imaging | 113091000 | 482 | 31.88% | 63,171 |
| Cerebrovascular accident | 230690007 | 371 | 24.54% | 4 |
| Global assessment of functioning -1993 Diagnostic and Statistical Manual of Mental Disorders-ver.4th | 284061009 | 361 | 23.88% | 0 |
| Systemic disease | 56019007 | 353 | 23.35% | 0 |
| Disorder of nervous system | 118940003 | 335 | 22.16% | 780,478 |
| Substance abuse | 66214007 | 279 | 18.45% | 9,466 |
| Parkinson’s disease | 49049000 | 275 | 18.19% | 0 |
| Impaired cognition | 386806002 | 260 | 17.20% | 13,375 |
| Seizure disorder | 128613002 | 240 | 15.87% | 28,586 |
| Hypersensitivity reaction | 421961002 | 218 | 14.42% | 4,686 |
| Schizophrenic disorders | 191526005 | 216 | 14.29% | 40777 |
| History of clinical finding in subject | 417662000 | 207 | 13.69% | 189,543 |
| Risk identification: childbearing family | 386414004 | 205 | 13.56% | 0 |
| Clinicaldementia rating scale | 273367002 | 204 | 13.49% | 0 |