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. 2018 Feb 19;5(5):233–248. doi: 10.15698/mic2018.05.630

Table 1.

Mutations identified from snf1∆ bypass suppressor CLS screen.

a Amino acid substitutions.

b Recessive (R) or semi-dominant (SD) growth phenotype on YEP+glycerol/ethanol plates.

c Mutation in the promoter.

d Frameshift mutation at A352 that creates a stop codon at codon 357.

Mutant Strain ORF Gene name Chr Mutation Changea Domb
A1-1 JS1413 YBR112C CYC8 II 464597 C/G A392P R
YHR118C ORC6 VIII 344796 C/G C278S
YMR218C TRS130 XIII 706605 C/G V95L
A1-2 JS1414 YBR112C CYC8 II 464597 C/G A392P R
YMR218C TRS130 XIII 706605 C/G V95L
A1-3 JS1415 YBR112C CYC8 II 464597 C/G A392P R
YMR218C TRS130 XIII 706605 C/G V95L
A2-1 JS1416 YBR112C CYC8 II 464762 C/T G337S SD
A2-2 JS1418 YBR112C CYC8 II 464662 A/C L370R R
YDR325W YCG1 IV 1119362 C/T A746V
A3-1 JS1422 YBR112C CYC8 II 464654 G/A L373F R
YPL212C PUS1 XVI 152608 C/G C181S
A3-2 JS1423 YBR112C CYC8 II 464654 G/A L373F R
YPL212C PUS1 XVI 152608 C/G C181S
YBR275C RIF1 II 755428 T/C N560S
A4-1 JS1424 YBR112C CYC8 II 464588 C/A D395Y SD
YMR153W NUP53 XIII 564421 C/T -14c
A4-2 JS1425 YBR112C CYC8 II 464588 C/A D395Y R
YMR153W NUP53 XIII 564421 C/T -14c
YBR098W MMS4 II 443160 G/A G549E
A5-1 JS1426 YBR112C CYC8 II 464723 A/C L350V SD
YBR112C CYC8 II 464715 ∆C A352d
A5-2 JS1427 YBR112C CYC8 II 464723 A/C L350V R
YBR112C CYC8 II 464715 ∆C A352d
A6-1 JS1417 YBR112C CYC8 II 464670 C/A W367C R
A6-2 JS1419 YBR112C CYC8 II 464670 C/A W367C R
A7-1 JS1430 YGL035C MIG1 VII 432935 C/A C43F SD
A8-2 JS1421 YBR112C CYC8 II 464660 C/T G371S SD
YJL129C TRK1 X 174668 T/C D880G
A9-1 JS1428 YBR112C CYC8 II 464660 C/T G371S R
A9-2 JS1429 YBR112C CYC8 II 464660 C/T G371S R
YIL015W BAR1 IX 323228 C/G P296R
A10-1 JS1431 YBR112C CYC8 II 464671 C/A W367L R
A10-2 JS1432 YBR112C CYC8 II 464671 C/A W367L R
YBR135W CKS1 II 504917 T/G L22V
YJR080C AIM24 X 581354 G/A S88F