Figure 1.

Phase I schematic.

The horizontal axis represents time (min) relative to the Vibralung treatment. Two randomized visits were performed where the participants breathed on the Vibralung device: one with sound and one without sound. Assessments were performed at the time points as marked by the grey arrows. Huff cough was performed every 30 min indicated by the black star.

PFT, pulmonary function; DL_CO/DL_NO, diffusion capacity of the lungs for carbon monoxide and nitric oxide; SpO₂, peripheral oxygen saturation; Survey, Likert survey to assess symptoms.