Table 2.
Study I and II population demographics and baseline pulmonary function.
| Study I | Study II | |||
|---|---|---|---|---|
| n | 10 | 11 | ||
| Sex (male) | 7 (70%) | 5 (45%) | ||
| Age (years) | 30 | (25–34) | 20* | (17–29) |
| Height (cm) | 170 | (159–176) | 163 | (160–168) |
| Weight (kg) | 63 | (54–79) | 59 | (50–65) |
| BMI (kg/m2) | 24 | (19–26) | 22 | (20–26) |
| VO2PEAK (ml/min/kg) | 19 | (10–24) | ||
| VO2PEAK (% predicted) | 59 | (30–61) | ||
| Pulmonary function | ||||
| FVC (l) | 4.1 | (2.8–4.8) | 3.1 | (2.7–3.4) |
| FVC (% predicted) | 89 | (75–98) | 76 | (65–88) |
| FEV1 (l/s) | 2.6 | (1.4–3.3) | 2.1 | (1.6–2.4) |
| FEV1 (% predicted) | 76 | (46–89) | 57 | (47–69) |
| FEV1/FVC (%) | 63 | (54–74) | 64 | (58–74) |
| FEF25–75 (l/s) | 1.3 | (0.5–2.7) | 1.2 | (0.7–1.6) |
| FEF25–75 (% predicted) | 33 | (14–67) | 27 | (18–46) |
Values are median, and the interquartile range is in brackets.
*
p < 0.05 versus study I Mann–Whitney U test.
BMI, body mass index; FVC, forced vital capacity; FEF25–75, forced expiratory volume at 25–75% of the FVC; FEV1, forced expiratory volume in 1 s of the FVC; VO2PEAK, maximal oxygen consumption.