Table 1. Characteristics of the study population at age 50 as a function of multimorbidity and mortality status at the end of follow-up (N = 8,270).

Characteristic	Cardiometabolic multimorbidity			Mortality
	No	Yes	p-Value	No	Yes	p-Value
N	7,759	511		6,864	1,406
Age, mean (SD)	50.2 (2.4)	51.0 (2.3)	<0.001	50.0 (2.3)	51.2 (2.5)	<0.001
Male	67.0	68.9	0.38	67.7	64.2	0.01
Non-white	9.2	25.8	<0.001	9.9	11.7	0.05
Single	24.5	22.3	0.26	23.7	27.9	0.001
No academic qualification	10.3	15.3	<0.001	10.1	12.9	<0.001
Low occupational position (clerical/support staff)	18.7	29.8	<0.001	17.7	27.7	<0.001
Physically inactivea	50.1	55.4	0.02	50.0	52.5	0.09
Poor dietb	37.5	44.8	0.001	36.4	45.2	<0.001
Alcohol abstention or heavy alcohol consumptionc	36.8	42.9	0.006	36.5	40.5	0.005
Current smoker	14.9	24.7	<0.001	12.9	28.6	<0.001
Hypertensiond	20.3	30.3	<0.001	19.1	29.5	<0.001
Overweight/obesitye	47.5	61.6	<0.001	47.8	51.2	0.02
Total cholesterol ≥ 5 mmol/l	86.6	90.6	0.01	86.7	87.8	0.27
Family history of diabetes or CVD	17.9	19.4	0.41	18.4	16.4	0.09

Data are percentages unless otherwise indicated.

^aCorresponds to <2.5 hours/week of moderate or vigorous physical activity (recommended level).

^bCorresponds to fruit and vegetable consumption < 1 serving/day.

^cHeavy alcohol consumption was defined as >14 units/week in women and >21 units/week in men, and alcohol abstention was defined as <1 unit/week.

^dBlood pressure ≥ 140/90 mm Hg or use of antihypertensive medication.

^eBMI ≥ 25 kg/m².

CVD, cardiovascular disease.