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. 2018 May 9;12(5):e0006474. doi: 10.1371/journal.pntd.0006474

Table 1. Neutralizing antibody titers and anti-RVFV total IgG adjusted SumOD ELISA results of plasma from vaccinated and control animals.

Inoculum rZH501-ΔNSs rZH501-ΔNSs-ΔNSm Sham Inoculated Controls
Mean PRNT50 ± STDEV Mean PRNT80 ± STDEV Anti-RVFV IgG mean SumOD ± STDEV Mean PRNT50 ± STDEV Mean PRNT80 ± STDEV Anti-RVFV IgG mean SumOD ± STDEV Mean PRNT50 ± STDEV Mean PRNT80 ± STDEV Anti-RVFV IgG mean SumOD ± STDEV
Day 7 post-vaccination 1:867 ± 393 1:<400 ± 0 0.004 ± 0.006 1:<400 ± 0 1:<400 ± 0 -0.005 ± 0.0477 1:<400 ± 0 1:<400 ± 0 0.008 ± 0.023
Day 14 post-vaccination 1:23,467 ± 14,964 1:3,533 ± 4,709 0.111 ± 0.105 1:10,933 ± 4,572 1:933 ± 547 0.0741 ± 0.045 1:<400 ± 0 1:<400 ± 0 -0.002 ± 0.013
Day 21 post-vaccination 1:59,733 ± 34,976 1:8,267 ± 9,407 0.382 ± 0.125 1:26,667 ± 20,001 1:6,400 ± 3,505 0.258 ± 0.193 1:<400 ± 0 1:<400 ± 0 -0.003 ± 0.007
Day 28 post-vaccination 1:29,867 ± 17,488 1:13,867 ± 6,292 0.689 ± 0.168 1:10,733 ± 8,647 1:3,000 ± 2,814 0.384 ± 0.225 1:<400 ± 0 1:<400 ± 0 0.009 ± 0.004
Day 35 post-vaccination 1:25,707 ± 15,989 1:7,333 ± 9,253 1.052 ± 0.289 1:10,667 ± 8,507 1:1,867 ± 2,286 0.749 ± 0.492 1:<400 ± 0 1:<400 ± 0 0.003 ± 0.023
Day 7 post-challenge 1:56,533 ± 39,331 1:15,200 ± 9,149 1.757 ± 0.459 1:34,133 ± 19,271 1:10,133 ± 4,253 1.553 ± 0.717 1:3,360 ± 5,311 1:800 ± 490 0.001 ± 0.007
Day 14 post-challenge 1:90,667 ± 70,390 1:32,533 ± 21,648 2.011 ± 0.748 1:72,533 ± 65,601 1:16,000 ± 7,838 1.659 ± 0.691 1:71,680 ± 28,043 1: 8,640 ± 5,724 0.378 ± 0.307
Day 21 post-challenge 1:78,933 ± 73,493 1:21,333 ± 17,013 1.482 ± 0.656 1:59,733 ± 71,802 1:17,067 ± 17,013 1.338 ± 0.675 1:184,320 ± 133,513 1:46,080 ± 33,378 1.294 ± 0.594
Day 28 post-challenge 1:36,267 ± 17,013 1: 9,067 ± 4,253 1.867 ± 1.013 1:14,933 ± 5,226 1:4,267 ± 1,652 1.374 ± 0.609 1:307,202 ± 289,635 1:97,280 ± 68,692 1.232 ± 0.417