Table 1.
Cohort Clinical Data
Maternal | Infant | GDM diagnostic criteria | Treatment | ||||||
---|---|---|---|---|---|---|---|---|---|
Study group | Age (years) | BMI (kg/m2) | Sex | Race/ethnicity | Birth weight (g) | Gestational age (weeks) | GCT | GTT | None/diet/oral/insulin |
Control | |||||||||
Control 1 | 33 | 22.7 | F | African American | 3,375 | 39 | Negative | n/a | None |
Control 2 | 31 | 24.3 | F | Hispanic | 3,820 | 39 | Negative | n/a | None |
Control 3 | 37 | 30.0 | F | Hispanic | 3,560 | 40.2 | n/a | Normal | None |
Control 4 | 24 | 27.7 | M | Hispanic | 3,395 | 38.5 | Positive | Normal | None |
Control 5 | 20 | 23.4 | M | African American | 3,005 | 38 | n/a | n/a | None |
Control 6 | 27 | 29.4 | F | Hispanic | 3,180 | 40.5 | Negative | n/a | None |
Mean | 28.7 ± 6.2 | 26.3 ± 3.2 | 3,389 ± 285 | 39.0 ± 1.0 | |||||
LGA-GDM | |||||||||
LGA-GDM 1 | 36 | 37.5 | M | Asian | 4,265 | 38.6 | Positive | n/a | Insulin |
LGA-GDM 2 | 28 | 40.2 | M | Hispanic | 4,495 | 39.5 | Positive | Abnormal | Diet |
LGA-GDM 3 | 32 | 44.8 | M | Hispanic | 3,965 | 39.4 | n/a | Abnormal | Diet |
LGA-GDM 4 | 21 | 35.7 | M | Asian | 4,320 | 40.3 | Positive | Abnormal | Diet |
LGA-GDM 5 | 41 | 38.5 | F | Hispanic | 3,800 | 39.2 | n/a | Abnormal | Oral |
LGA-GDM 6 | 36 | 34.0 | F | Hispanic | 4,505 | 40.6 | Negative | Abnormal | Diet |
Mean | 32.3 ± 7.1 | 38.4 ± 3.8a | 4,225 ± 286a | 39.6 ± 0.7 |
Clinical data of Control and LGA-GDM cohorts. Mean age, weight, BMI, birth weight, and gestational age, represented as mean ± standard deviation.
P value <0.05 measured by student's t-test.
BMI, body mass index; GCT, glucose challenge test; GDM, gestational diabetes mellitus; GTT, glucose tolerance test.