Table 3.

Comparison of women under 45 years of age with stage I disease who had or had not undergone fertility preservation (N=76)

Variable	Fertility Preservation		p*
	No	Yes
	44	32
Center
MSK	3 (7%)	6 (19%)	0.013
GRCC	33 (75%)	26 (81%)
DEN	8 (18%)	0 (0%)
Age at Diagnosis
Median	38	26	<0.001
Range	17–45	15–40
Smoker (6 missing)
Yes	10 (25%)	8 (27%)	1
Capsule Rupture (2 missing)
Yes	13 (30%)	16 (52%)	0.091
Cytology**
Yes	41 (93%)	32 (100%)	–
Positive Cytology (1 missing)**
Yes	4 (10%)	0 (0%)	–
Appendectomy (3 missing)
Yes	35 (85%)	27 (84%)	1
Omentectomy**
Yes	41 (93%)	31 (97%)	–
Pelvic Lymphadenectomy (1 missing)
Yes	17 (39%)	13 (41%)	1
Median	13	14	0.967
Range	5–33	1–34
Para-aortic Lymphadenectomy (1 missing)
Yes	15 (34%)	16 (50%)	0.237
Median	13	8.5	0.1
Range	2–42	2–29
Grade (20 missing)**
G1	22 (69%)	18 (75%)	0.767
G2/G3	10 (31%)	6 (25%)
Chemotherapy***
Yes	14 (39%)	6 (19%)	0.109
Median Number of Cycles	6	5	0.175
Range	4–8	3–9
Chemotherapy Regimen Type***
Gynecologic	11 (79%)	4 (67%)	0.613
Gastrointestinal	3 (21%)	2 (33%)
Upper GI Endoscopy***
Yes	8 (22%)	6 (19%)	0.722
Lower GI Endoscopy***
Yes	11 (31%)	4 (12.5%)	0.087
Combined Upper and Lower GI Endoscopy***
Yes	12 (33%)	6 (19%)	0.271
CA125 >35 U/mL*** (24 missing)
Yes	8 (35%)	5 (24%)	0.518
Tumor Size, cm*** (10 missing)
Median	13	15	0.533
Range	8–30	4.5–36

GCCR, Gustave Roussy Cancer Campus; DEN, Rigshospitalet in Denmark; MSK = Memorial Sloan Kettering Cancer Center; GI = gastrointestinal

^*p values were obtained using the Wilcoxon rank sum test for continuous variables and the Fisher exact test for categorical variables

^**A p value is not provided if there were less than 5 patients within a group.

^***MSK and GRCC data available (N=68)