Table 4.

Longitudinal change in mean T2 values in diabetics with severe disease and non-diabetics.

Absolute change in T2 values over 2 years – Severe-Diabetics
	Severe-Diabetics (n=38)		Non-diabetics (n=159)
	Adjusted means	[95% CI]	Adjusted means	[95% CI]	Effect size [95% CI]*	p-value
Absolute change in mean T2 values
Global knee T2	1.29	[0.76,1.83]	1.07	[0.80,1.35]	0.22 [−0.40,0.83]	0.482
PAT T2	1.55	[0.55,2.54]	1.34	[0.84,1.84]	0.21 [−0.82,1.24]	0.682
MT T2	1.29	[0.48,2.09]	1.26	[0.90,1.63]	0.03 [−0.90,0.95]	0.960
LT T2	1.52	[0.86,2.17]	1.33	[0.96,1.70]	0.19 [−0.64,1.01]	0.652
MF T2	0.71	[0.01,1.41]	0.46	[0.09,0.83]	0.25 [−0.54,1.04]	0.536
LF T2	1.43	[0.61,2.25]	1.47	[1.13,1.81]	−0.04 [−0.94,0.85]	0.920

Data are given as adjusted means, corrected for race, age, sex, baseline BMI, baseline KL score, with [95% confidence intervals] and computed as the absolute change between the 24-months and the baseline

^*Effect size for difference in T2 and texture parameters between groups; P-values <0.05 are in bold. PAT = patella, MT = medial tibia, LT = lateral tibia, MF = medial femur, LF = lateral femur.