Table 3.

Serial changes of serum and urinary markers

Parameter	Patients with AKI	Patients without AKI	P-value
SCr (μmol/L)
Pre PCI	87.19±29.88	84.82±29.55
24 h after PCI	110.33±38.94	87.90±27.28
48 h after PCI	135.79±53.99**	90.02±29.74*
A relative measurement at 24 h after PCI	1.30±0.26	1.07±0.19	0.001
uL-FABP (μg/g Cr)
Pre PCI	1.92 (1.23–3.22)	3.93 (1.48–5.55)
6 h after PCI	4.31 (2.22–6.75)**	4.62 (1.96–6.96)**
24 h after PCI	6.64 (5.92–9.40)**	4.63 (2.22–8.19)**
48 h after PCI	5.85 (2.75–8.65)**	4.78 (2.01–7.42)*
A relative measurement at 6 h after PCI	1.95 (1.69–2.21)	1.18 (1.01–1.75)	0.001
A relative measurement at 24 h after PCI	3.13 (2.64–5.48)	1.39 (1.10–1.89)	<0.001
uNGAL (μg/g Cr)
Pre PCI	25.20 (11.25–55.62)	59.69 (39.81–85.98)
6 h after PCI	88.05 (45.22–248.75)**	56.32 (37.63–122.26)
24 h after PCI	104.05 (50.08–162.82)**	60.69 (33.86–112.10)
48 h after PCI	103.15 (40.83–178.27)**	61.86 (35.41–118.14)
A relative measurement at 6 h after PCI	4.30 (2.02–4.93)	1.12 (0.66–1.80)	<0.001
A relative measurement at 24 h after PCI	3.22 (1.72–5.53)	1.09 (0.60–2.03)	<0.001
uKIM-1 (μg/g Cr)
Pre PCI	1.24 (0.46–2.64)	1.10 (0.70–1.57)
6 h after PCI	1.21 (0.50–2.66)	1.18 (0.66–1.57)
24 h after PCI	1.72 (1.16–7.08)	1.21 (0.64–1.68)
48 h after PCI	2.08 (1.18–7.74)*	1.07 (0.78–1.76)
A relative measurement at 6 h after PCI	1.08 (0.71–1.53)	0.98 (0.81–1.47)	0.896
A relative measurement at 24 h after PCI	2.91 (0.86–7.13)	1.11 (0.75–1.53)	0.049

SCr: serum creatinine; Cr: creatinine; uL-FABP: urinary liver-type fatty acid-binding protein; uNGAL: urinary neutrophil gelatinase-associated lipocalin; uKIM-1: urinary kidney injury molecule-1; PCI: percutaneous coronary intervention; AKI: acute kidney injury. Data are presented as the mean±SD or medians with interquartile ranges (25%–75%). Values that are significantly different between pre-and post-PCI are indicated by

^* P<0.05,

^** P<0.01