Table 2.
Treatment | Dose (mg/kg) | LDH |
Creatinine-Kinase |
Creatinine (mg/dl) |
Urea (nmol/l) |
Uric acid (mg/dl) |
|||||
---|---|---|---|---|---|---|---|---|---|---|---|
Mean ± S.E | % | Mean ± S.E | % | Mean ± S.E | % | Mean ± S.E | % | Mean ± S.E | % | ||
Control | – | 113.32 ± 4.70 | 183.66 ± 5.01 | 0.91 ± 0.0 | 36.90 ± 1.79 | 1.92 ± 0.04 | |||||
CCl4a | 1.25 mL/kg | 198.31 ± 7.12*** | 325.16 ± 11.00*** | 3.10 ± 0.14*** | 192.33 ± 8.34*** | 6.44 ± 0.21*** | |||||
SI + CCl4b | 10 | 152.80 ± 11.32** | 23 | 195.50 ± 8.64*** | 39 | 1.84 ± 0.05*** | 40 | 126.66 ± 6.53*** | 34 | 2.83 ± 0.1*** | 56 |
HFb | 12 | 210.66 ± 7.93 | 6 | 266.33 ± 8.19** | 18 | 2.65 ± 0.13 | 14 | 161.00 ± 715* | 16 | 5.40 ± 0.26* | 16 |
GLb | 84 | 157.92 ± 11.96* | 20 | 270.83 ± 7.75** | 17 | 3.09 ± 0.07 | – | 160.66 ± 7.97* | 16 | 5.11 ± 0.27** | 21 |
HF + GLb | 6 + 42 | 168.47 ± 9.74* | 15 | 212.16 ± 7.43*** | 35 | 2.11 ± 0.07*** | 32 | 148.66 ± 7.49** | 23 | 4.55 ± 0.28*** | 29 |
HF + GLb | 12 + 84 | 162.44 ± 4.41** | 18 | 203.333 ± 9.76*** | 37 | 2.05 ± 0.04*** | 34 | 143.00 ± 6.26*** | 23 | 3.16 ± 0.24*** | 51 |
All values represent mean ± SEM.
LDH: Lactate dehydrogenase.
As compared with Control group.
As compared with CCl4 only group.
p < .05;
p < .01;
p < .001; ANOVA, followed by Dunnett's multiple comparison test.